R: Simulates SPSO and Efftox Phase 12 Trials with Correlated Outcomes

# Simulates SPSO and Efftox Phase 12 Trials with Correlated Outcomes

## Documentation for package ‘Phase12Compare’ version 1.5

- DESCRIPTION file.

## Help Pages

AssignEffTox | Determines the optimal dose to assign the next patient cohort.
AssignEffToxUT | Determines the optimal dose to assign the next patient cohort.
GETBIN | Generate binary bivariate data.
GetDesire | Returns the desireability value of a dose.
GetEfftoxContour | Assigns next patient cohort based on the Efftox model with a Desirability based objective function.
GetEfftoxUt | Assigns next patient cohort based on the Efftox model with a Utility based objective function.
GetPriorsSPSO | Returns prior dose-specific means and prior ESS for the SPSO model.
GetSpsoContour | Assigns next patient cohort based on the SPSOP model with a Utility based objective function.
GetSpsoUt | Assigns next patient cohort based on the SPSOP model with a Utility based objective function.
ReturnOpt | Obtains optimal dose level.
RunAdaptiveEffToxTrialCORR | Simulates utility based Efftox trials
RunAdaptiveEffToxTrialCORRCONTOUR | Simulates desirability based Efftox trials
SimEfftoxContour | Simulates trial replications from the Efftox model with desirability optimality function.
SimEfftoxUt | Simulates trial replications from the Efftox model with utility optimality function.
SimSpsoContour | Simulates trial replications from the SPSO model with desirability optimality function.
SimSpsoUt | Simulates trial replications from the SPSO model with desirability optimality function.
UTEFFTOX | Samples from the posterior of the utility based phase12 model.