ubiquity: PKPD, PBPK, and Systems Pharmacology Modeling Tools
Complete work flow for the analysis of pharmacokinetic pharmacodynamic (PKPD), physiologically-based pharmacokinetic (PBPK) and systems pharmacology models including: creation of ordinary differential equation-based models, pooled parameter estimation, individual/population based simulations, rule-based simulations for clinical trial design and modeling assays, deployment with a customizable 'Shiny' app, and non-compartmental analysis. System-specific analysis templates can be generated and each element includes integrated reporting with 'PowerPoint' and 'Word'.
| Version: | 2.1.0 |
| Depends: | R (≥ 4.2.0) |
| Imports: | cli, deSolve, dplyr (≥ 1.0.0), digest, doParallel, flextable, foreach, ggplot2, knitr, MASS, onbrand (≥ 1.0.2), optimx, PKNCA, pso, readxl, rmarkdown, rhandsontable, scales, stats, stringr, shiny |
| Suggests: | babelmixr2, GA, GGally, gridGraphics, gridExtra, grid, officer, rxode2, webshot, ggrepel, rstudioapi, testthat |
| Published: | 2025-01-07 |
| DOI: | 10.32614/CRAN.package.ubiquity |
| Author: | John Harrold 
[aut, cre] |
| Maintainer: | John Harrold <john.m.harrold at gmail.com> |
| BugReports: | https://github.com/john-harrold/ubiquity/issues |
| License: | BSD_2_clause + file LICENSE |
| URL: | https://r.ubiquity.tools |
| NeedsCompilation: | no |
| SystemRequirements: | Perl |
| Citation: | ubiquity citation info |
| Materials: | README, NEWS |
| In views: | Pharmacokinetics |
| CRAN checks: | ubiquity results |
Documentation:
| Reference manual: | ubiquity.html , ubiquity.pdf |
| Vignettes: |
Deployment (source, R code) Estimation (source, R code) Language (source, R code) Report Generation (source, R code) Simulation (source, R code) Titration/Rule-Based Simulations (source, R code) |
Downloads:
| Package source: | ubiquity_2.1.0.tar.gz |
| Windows binaries: | r-devel: ubiquity_2.1.0.zip, r-release: ubiquity_2.1.0.zip, r-oldrel: ubiquity_2.1.0.zip |
| macOS binaries: | r-release (arm64): ubiquity_2.1.0.tgz, r-oldrel (arm64): ubiquity_2.1.0.tgz, r-release (x86_64): ubiquity_2.1.0.tgz, r-oldrel (x86_64): ubiquity_2.1.0.tgz |
| Old sources: | ubiquity archive |
Reverse dependencies:
| Reverse suggests: | ruminate |
Linking:
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