ldsep 2.1.6
- Remove dependency on C++11.
ldsep 2.1.5
- Bug fix: Use &&instead of&in C++ source.
ldsep 2.1.4
- Use unnamed formula argument in aggregate()to account
for change in R.
ldsep 2.1.2
- DOUBLE_EPS->- DOUBLE_EPSILON.
- Modified citation to point to Heredity.
- Adds notes about the necessity of using adaptive priors in
ldfast().
ldsep 2.1.0
- Includes a winargument inldfast(), which
implements the moment-based LD correction along a sliding window.
- Fixes a bug where monomorphic SNPs were causing errors when
type = "Dprime"was selected inldfast(). Now
we just returnNA’s for LD with monomorphic SNPs.
- Uses the complete reference of Gerard (2021)
(doi:10.1111/1755-0998.13349)
ldsep 2.0.2
- Removes ldfast_old()andldfast_calc(),
which were not used in any exported functions, because these functions
had memory issues, detected by valgrind.
ldsep 2.0.1
- Added ldfast(), a new LD estimation approach based on
sample moments of marginal posterior genotype moments.
- Unlike ldest(),mldest(), andsldest(), the new approach implemented inldfast()is scalable to genome-wide applications, as these
new estimators can be calculated in linear time in the sample size.
- Citation of MLE approach points to MER article.
ldsep 1.1.0
- I have changed the terminology from “gametic LD” to “haplotypic” LD,
and so all instances of “gametic” have changed to “haplotypic”. A
breaking change is that all options that were "gam"are now"hap".
- Fixed an issue where the title in plot.lddf()was being
cut off.
- Added a reference to the preprint where the methodology is
developed.
- Updated the vignette to also take a user through uploading a VCF
file into R using the VariantAnnotationpackage. We also
provided examples on formatting genotype likelihoods fromupdogandfitpoly.
ldsep 1.0.0
- Initial release of package.