graposas: Graphical Approach Optimal Sample Size
Graphical approach provides a useful framework for multiplicity adjustment in clinical trials with multiple endpoints. This package includes statistical methods to optimize sample size over initial weight and transition probability in a graphical approach under a common setting, which is to use marginal power for each endpoint in a trial design.
    See Zhang, F. and Gou, J. (2023). Sample size optimization for clinical trials using graphical approaches for multiplicity adjustment, Technical Report.
| Version: | 1.0.0 | 
| Depends: | R (≥ 4.2.0) | 
| Imports: | GA (≥ 3.0.0), graphics (≥ 4.2.0), mvtnorm (≥ 1.1.0), stats (≥ 4.0.0) | 
| Published: | 2023-08-17 | 
| DOI: | 10.32614/CRAN.package.graposas | 
| Author: | Jiangtao Gou [aut, cre],
  Fengqing (Zoe) Zhang [aut] | 
| Maintainer: | Jiangtao Gou  <gouRpackage at gmail.com> | 
| License: | GPL-3 | 
| NeedsCompilation: | no | 
| CRAN checks: | graposas results | 
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