SubgrpID: Patient Subgroup Identification for Clinical Drug Development
Implementation of Sequential BATTing (bootstrapping and aggregating of thresholds from trees) for developing threshold-based multivariate (prognostic/predictive) biomarker signatures. Variable selection is automatically built-in. Final signatures are returned with interaction plots for predictive signatures. Cross-validation performance evaluation and testing dataset results are also output. Detail algorithms are described in Huang et al (2017) <doi:10.1002/sim.7236>.
| Version: |
0.12 |
| Imports: |
glmnet, MASS, rpart, survival, Matrix, ggplot2 |
| Published: |
2024-02-03 |
| DOI: |
10.32614/CRAN.package.SubgrpID |
| Author: |
Xin Huang [aut, cre, cph],
Yan Sun [aut],
Saptarshi Chatterjee [aut],
Paul Trow [aut] |
| Maintainer: |
Xin Huang <xin.huang at abbvie.com> |
| License: |
GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| NeedsCompilation: |
no |
| CRAN checks: |
SubgrpID results |
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