SpaCCI: Spatially Aware Cell-Cell Interaction Analysis
Provides tools for analyzing spatial cell-cell interactions based on ligand-receptor pairs, including functions for local, regional, and global analysis using spatial transcriptomics data. Integrates with databases like 'CellChat' <http://www.cellchat.org/>, 'CellPhoneDB' <https://www.cellphonedb.org/>, 'Cellinker' <https://www.rna-society.org/cellinker/index.html>, 'ICELLNET' <https://github.com/soumelis-lab/ICELLNET>, and 'ConnectomeDB' <https://humanconnectome.org/software/connectomedb/> to identify ligand-receptor pairs, visualize interactions through heatmaps, chord diagrams, and infer interactions on different spatial scales.
| Version: |
1.0.4 |
| Depends: |
R (≥ 3.5.0) |
| Imports: |
Rcpp (≥ 1.0.13), Seurat (≥ 4.0.0), nnls, ggrepel, pheatmap, circlize (≥ 0.4.12), Matrix, dplyr, patchwork, grDevices, reshape2, graphics, ggplot2, FNN |
| LinkingTo: |
Rcpp, RcppArmadillo |
| Published: |
2025-05-12 |
| DOI: |
10.32614/CRAN.package.SpaCCI |
| Author: |
Li-Ting Ku [aut, cre] |
| Maintainer: |
Li-Ting Ku <lku at mdanderson.org> |
| License: |
GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| NeedsCompilation: |
yes |
| CRAN checks: |
SpaCCI results |
Documentation:
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