RCNA: Robust Copy Number Alteration Detection (RCNA)
Detects copy number alteration events in targeted exon sequencing
data for tumor samples without matched normal controls. The advantage of
this method is that it can be applied to smaller sequencing panels including
evaluations of exon, transcript, gene, or even user specified genetic
regions of interest. Functions in the package include steps for GC-content
correction, calculation of quantile based normal karyotype ranges,
and calculation of feature score. Cutoffs for "normal" quantile and score
are user-adjustable.
| Version: |
1.0 |
| Depends: |
R (≥ 3.5.0) |
| Imports: |
doParallel, methods, utils, modeest, data.table, foreach, R.utils |
| Suggests: |
knitr, rmarkdown, usethis |
| Published: |
2024-12-03 |
| DOI: |
10.32614/CRAN.package.RCNA |
| Author: |
Matt Bradley [aut, cre] |
| Maintainer: |
Matt Bradley <mbradley at emmes.com> |
| License: |
GPL-3 |
| NeedsCompilation: |
no |
| Materials: |
README, NEWS |
| CRAN checks: |
RCNA results |
Documentation:
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