Clinical trial design for subgroup selection in three-stage group sequential trial as described in Lai, Lavori and Liao (2014, <doi:10.1016/j.cct.2014.09.001>). Includes facilities for design, exploration and analysis of such trials. An implementation of the initial DEFUSE-3 trial is also provided as a vignette.
| Version: | 1.4.3 |
| Imports: | R6, mvtnorm, knitr, magrittr, dplyr |
| Suggests: | rmarkdown |
| Published: | 2022-12-02 |
| DOI: | 10.32614/CRAN.package.ASSISTant |
| Author: | Tze Leung Lai [ctb], Philip Lavori [aut], Olivia Liao [aut], Balasubramanian Narasimhan [aut, cre], Ka Wai Tsang [aut] |
| Maintainer: | Balasubramanian Narasimhan <naras at stat.Stanford.EDU> |
| BugReports: | https://github.com/bnaras/ASSISTant/issues |
| License: | GPL-2 | GPL-3 [expanded from: GPL (≥ 2)] |
| URL: | https://github.com/bnaras/ASSISTant |
| NeedsCompilation: | no |
| Materials: | README, NEWS |
| In views: | ClinicalTrials |
| CRAN checks: | ASSISTant results |
| Reference manual: | ASSISTant.html , ASSISTant.pdf |
| Vignettes: |
Adaptive Subgroup Selection in Sequential Trials (source, R code) Design of the DEFUSE3 Trial (source, R code) Using Discrete Rankin Scores (source, R code) |
| Package source: | ASSISTant_1.4.3.tar.gz |
| Windows binaries: | r-devel: ASSISTant_1.4.3.zip, r-release: ASSISTant_1.4.3.zip, r-oldrel: ASSISTant_1.4.3.zip |
| macOS binaries: | r-release (arm64): ASSISTant_1.4.3.tgz, r-oldrel (arm64): ASSISTant_1.4.3.tgz, r-release (x86_64): ASSISTant_1.4.3.tgz, r-oldrel (x86_64): ASSISTant_1.4.3.tgz |
| Old sources: | ASSISTant archive |
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